For instance, they recognized 812 ladies who had the identical mutation in one in all their two copies of the MC3R gene. This mutation solely partly lowered the power of the receptor to work. Regardless of this refined impact, ladies who carried this had been on common 4.7 months older at puberty than these with out the mutation.
Individuals with mutations that lowered the operate of MC3R had been additionally shorter and had decrease quantities of lean tissue, similar to muscle, nevertheless it had no affect on how a lot fats they carried.
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