Subsequent, the researchers estimated total breast most cancers danger, in accordance with whether or not the ladies had or hadn’t gone via the menopause; and by most cancers sort (optimistic for oestrogen or progesterone, or HER-2, or optimistic/damaging for all 3 hormones), stage (dimension and extent of tumour unfold), and grade (diploma of tumour cell abnormality).
These case-control teams comprised: 23,999 pre/peri-menopausal ladies with invasive breast most cancers and 17,686 ladies with out; 45,839 postmenopausal ladies with breast most cancers and 36,766 with out.
In all, there have been 46,528 oestrogen receptor optimistic tumours and 11,246 controls; 34,891 progesterone receptor optimistic tumours and 16,432 controls; 6,945 HER2 optimistic tumours and 33,214 controls; 1,974 triple optimistic circumstances; and 4,964 triple damaging circumstances.
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