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Tag: genetic
How can genetic algorithms be applied to supply chain optimization?
Genetic Algorithms (GA) are a particular set of evolutionary algorithms, these algorithms attempt to simulate the evolution of biology evolution however within the area of numbers. The genetic algorithm is among the instruments that can be utilized to use evolutionary computing strategies to seek out good, typically even optimum, options to issues which have billions… Continue reading How can genetic algorithms be applied to supply chain optimization?
A rapidly reversible mutation generates subclonal genetic diversity and unstable drug resistance
Completely different mechanisms of adaptation have completely different timescales. Epigenetic adjustments are sometimes fast and reversible, whereas most genetic adjustments have almost negligible charges of reversion (1). This poses a problem for genetic adaptation to transient circumstances corresponding to drug therapy; mutations that confer drug resistance are sometimes deleterious within the absence of drug, and… Continue reading A rapidly reversible mutation generates subclonal genetic diversity and unstable drug resistance
A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes
1. Weber, S., Ramirez, C. & Doerfler, W. Sign hotspot mutations in SARS-CoV-2 genomes evolve because the virus spreads and actively replicates in numerous elements of the world. Virus Res. 289, 198170 (2020). CAS PubMed PubMed Central Article Google Scholar 2. Sekowska, A., Wendel, S., Fischer, E. C. & Nørholm, M. H. H. Technology of… Continue reading A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes