During the last 10 years, researchers in The Gambia have utilised an ‘experiment of nature’ to research mechanisms underlying DOHaD phenomena.
In these subsistence farming communities, people conceived at totally different occasions of the yr expertise huge variation in vitamin throughout early improvement. We and the researchers investigated its potential impact of this and located it impacted their DNA, particularly .
The researchers investigated hyperlinks between this seasonality and ‘DNA methylation’ – a molecular marking system of DNA that may flip genes on or off.
Over time we’ve recognized many genes in kids during which their mom’s weight-reduction plan in early being pregnant, across the time of conception, seems to affect DNA methylation.
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