PAX8 alternation methylation within the kids was additionally related to their mom’s vitamin across the time of conception, particularly with circulating ranges of nutritional vitamins B6, B12, homocysteine, and cysteine.
Put collectively, these thrilling outcomes provide a tantalising glimpse of a hyperlink between early vitamin and later well being, on this case thyroid operate and thyroid-related well being outcomes.
What does this imply for public well being?
Nicely, proper now there are nonetheless many items of the puzzle to place collectively, together with confirming that particular vitamins straight affect the PAX8 gene within the early embryo, and that this persists into childhood and past.
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