Tag: infection

Resistance of Dickeya solani strain IPO 2222 to lytic bacteriophage ΦD5 results in fitness tradeoffs for the bacterium during infection

Campbell, A. The way forward for bacteriophage biology. Nat. Rev. Genet. 4, 471–477. https://doi.org/10.1038/nrg1089 (2003). CAS  Article  PubMed  PubMed Central  Google Scholar  Cheetham, B. F. & Katz, M. E. A task for bacteriophages within the evolution and switch of bacterial virulence determinants. Mol. Microbiol. 18, 201–208. https://doi.org/10.1111/j.1365-2958.1995.mmi_18020201.x (1995). CAS  Article  PubMed  Google Scholar  Mann, N.… Continue reading Resistance of Dickeya solani strain IPO 2222 to lytic bacteriophage ΦD5 results in fitness tradeoffs for the bacterium during infection

Evolution during primary HIV infection does not require adaptive immune selection

Significance HIV evolution inside contaminated people creates massive obstacles to profitable vaccination and remedy. Right here, we used a mannequin that matches viral masses and mutation charges to characterize the driving forces behind HIV evolution early throughout an infection. Surprisingly, the most effective mannequin of the info didn’t require express strain from the host immune… Continue reading Evolution during primary HIV infection does not require adaptive immune selection