Modified nucleotides used in COVID-19 vaccines work as designed – The Source

Hani Zaher
Zaher

To not fear, because it seems. A brand new research from Washington College in St. Louis finds that the N1-methylpseudouridine used within the COVID-19 mRNA vaccines is translated faithfully. The analysis, revealed in Cell Reports, was led by scientists within the laboratory of Hani Zaher, affiliate professor of biology in Arts & Sciences.

“Mobile mRNAs don’t usually have N1-methylpseudouridine,” stated Kyusik Kim, a graduate pupil within the molecular cell biology program, first writer of the research. “We discovered that the presence of N1-methylpseudouridine in mRNAs doesn’t appear to result in will increase within the variety of errors throughout translation.

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